Written by:
Arthi T
Cancer is a major health challenge in India, causing significant illness and death. To tackle this issue, clinical trials are essential for discovering new and improved cancer treatments. These trials not only help in finding better therapies but also provide patients with access to the latest treatments that might otherwise be unavailable. In this article, we will explore some of the leading institutions in India conducting cancer clinical trials and highlight the benefits of participating in these trials. By understanding the importance of clinical trials, we can appreciate the advancements in cancer care and how they are shaping the future of medical science in India.
According to the Lancet Regional Health journal, ‘over the past few decades, India’s participation in global clinical trials has grown, due in part to the size of the patient population, low operational costs, regulatory reforms, and the changing economic environment.’
What is a clinical trial?
A clinical trial is a research method used to find the best possible treatment for any cancer. All the best currently available cancer treatments are the result of previous clinical trials. In order to find new, better cancer treatments, clinical trials are compulsory.
Here’s an example of clinical trial
Imagine a patient with an advanced black tumor, typically treated with a combination of surgery and chemotherapy. This conventional treatment often leads to moderate success but comes with significant side effects and a lengthy recovery period. Recently, a novel targeted therapy has been developed that can precisely attack cancer cells while sparing healthy tissue. This new treatment promises improved survival rates with minimal side effects and a shorter recovery time.
To determine if this new drug works as promised, it must be administered to humans under close supervision and compared to the existing treatment (chemotherapy). This process is known as a clinical trial. During the clinical trial, patients receive the new treatment, and their cancer response is meticulously documented. If the new treatment delivers superior outcomes compared to the old treatment, it will become the new standard for treating advanced black tumor.
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Who makes sure that the patient is not harmed by participating in a clinical trial?
All cancer clinical trials in India need approval and monitoring by regulatory authorities approved by the Government of India such as Drug Controller General of India and ethics committees. They watch over these trials closely and make sure that participants are not harmed or put at unnecessary risk as part of the trial.
What are the types of clinical trials available?
Randomized trial
In this trial, half the patients receive the old cancer treatment and half receive the new cancer treatment and these two groups are compared to each other. Which arm one particular patient falls into is completely random.
Benefits of participating in a cancer clinical trial
Participating in clinical trials offers patients access to new drugs and treatments that they might not otherwise have. For example, stage 4 lung cancer patients who only receive chemotherapy typically live less than a year. However, those in clinical trials for targeted therapy or immunotherapy have survived for many years with few or no side effects.
Another benefit is free treatment. Many new cancer treatments are very expensive, sometimes costing lakhs per month. By joining a clinical trial, patients can get these costly drugs at no charge.
Clinical trials also ensure close monitoring. They are approved only after rigorous supervision by government and non-government agencies, so patients receive the best possible care.
Participating in clinical trials helps advance medical science. The effective treatments we have today are thanks to clinical trials conducted in the past.
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Who can participate?
All clinical trials have rules about who can and cannot participate. These rules are called “eligibility criteria” but may also be referred to as inclusion/exclusion criteria. The criteria are based on factors such as age, gender, the type and stage of a disease, previous treatment history, and other medical conditions. The eligibility criteria define the patient population that is being studied and are designed to protect the safety of participants in the trial. Because of the criteria, not everyone will qualify to participate in the trial.
Here are some prominent institutions in India that conduct cancer clinical trials:
Tata Memorial Centre (Mumbai):
Clinical research in cancer is one of the avowed objectives of Tata Memorial Centre and DAE funded cancer centres (DAEFCC). Numerous clinical research projects including several randomized clinical trials are currently in progress. The Institutes have a well established Scientific Review Committee and Ethics Committee. The projects will be approved by the Ethics Committee, which comprises members from a wide spectrum of society to include not only oncologists and medical doctors but also special scientists, philosophers and lay individuals. It is only when ethics approval is obtained that a project will be allowed to be undertaken by the investigator.
All India Institute of Medical Sciences (AIIMS- New Delhi)
AIIMS Delhi is a hub for clinical trials, including those focused on oncology. The institute conducts a wide range of clinical trials aimed at developing and evaluating new cancer treatments, including chemotherapy, immunotherapy, and targeted therapy. These trials are meticulously designed and supervised by experienced oncologists and researchers, ensuring the highest standards of patient care and scientific integrity. AIIMS Delhi collaborates with various national and international organizations to advance cancer research, providing patients with access to the latest experimental treatments and contributing significantly to global medical knowledge. The institute’s robust infrastructure, state-of-the-art facilities, and multidisciplinary approach make it a leading center for cancer clinical trials in India.
National Cancer Institute (Jhajjar, Haryana)
The National Cancer Institute is an extension of the All India Institute of Medical Sciences (AIIMS) and is dedicated to providing advanced cancer care and conducting cutting-edge research. The institute is equipped with state-of-the-art facilities, including advanced imaging technology, radiation therapy, surgical oncology, and specialized laboratories for molecular and genetic research. NCI Jhajjar conducts numerous clinical trials, focusing on innovative cancer treatments such as immunotherapy, targeted therapy, and personalized medicine. By fostering collaborations with leading national and international research organizations, NCI Jhajjar plays a pivotal role in advancing cancer research and offering patients access to the latest experimental therapies.
Rajiv Gandhi Cancer Institute and Research Centre (New Delhi)
RGCIRC is deeply involved in clinical research, conducting a wide array of clinical trials to explore new treatment modalities, improve existing therapies, and enhance patient outcomes. The research center collaborates with global oncology networks and pharmaceutical companies, ensuring access to the latest clinical trials and cutting-edge treatments. The institute’s multidisciplinary team of oncologists, researchers, and healthcare professionals is dedicated to delivering personalized care, integrating the latest scientific advancements into patient treatment plans.
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Kidwai Memorial Institute of Oncology in Bangalore
Kidwai Institute is also a hub for clinical research and trials, focusing on the development of new cancer therapies and improving existing treatment protocols. Its state-of-the-art facilities include specialized laboratories for molecular and genetic research, advanced imaging technology, and cutting-edge radiation therapy equipment. The institute collaborates with national and international research organizations, contributing significantly to the global fight against cancer. With a dedicated team of oncologists, researchers, and healthcare professionals, Kidwai Memorial Institute of Oncology is committed to advancing cancer treatment, improving patient outcomes, and providing compassionate care.
Adyar Cancer Institute in Chennai
This is one of India’s oldest and most esteemed cancer treatment and research centers. Adyar Cancer Institute is well-known for its commitment to providing affordable cancer care, making it accessible to patients from all socio-economic backgrounds. The institute is actively involved in clinical research, conducting numerous clinical trials to explore innovative treatments and improve patient outcomes. It collaborates with leading national and international research organizations, contributing significantly to global cancer research. With a multidisciplinary team of experts and a patient-centered approach, Adyar Cancer Institute continues to be a beacon of hope for cancer patients, dedicated to advancing the field of oncology and delivering exceptional care.
Christian Medical College (CMC), Vellore
CMC is actively engaged in clinical trials and cancer research, focusing on innovative therapies and improving patient care. CMC’s multidisciplinary approach ensures that patients receive holistic care tailored to their specific needs. With collaborations with leading global research organizations, CMC remains at the forefront of medical advancements, providing patients access to the latest treatments and contributing significantly to the field of oncology.
Amrita Institute of Medical Sciences (AIMS), Kochi
AIMS is actively involved in clinical trials, focusing on novel cancer treatments and personalized medicine. The institute’s commitment to research and innovation ensures that patients have access to the latest therapeutic options. With a dedicated team of oncologists, researchers, and healthcare professionals, AIMS is at the forefront of cancer treatment, offering high-quality care and advancing the field of oncology through rigorous scientific research.
Apollo Hospitals (Multiple Locations)
Apollo Hospitals, a renowned healthcare network in India, has multiple locations equipped with advanced oncology departments. The network is heavily involved in clinical trials, exploring new treatments and improving existing protocols. Apollo Hospitals collaborate with leading global research institutions, ensuring patients have access to the latest innovations in cancer care. Their multidisciplinary teams of oncologists, researchers, and healthcare professionals are dedicated to providing personalized care, enhancing patient outcomes, and advancing medical knowledge through continuous research and clinical excellence.
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Max Super Specialty Hospital, New Delhi
The hospital is actively engaged in clinical trials, focusing on cutting-edge cancer treatments and improving patient outcomes. Max Hospital collaborates with national and international research organizations, ensuring patients have access to the latest therapeutic options. With state-of-the-art facilities and a team of experienced oncologists and researchers, Max Hospital is dedicated to providing high-quality care, advancing cancer treatment, and contributing to medical research.
Fortis Memorial Research Institute, Gurgaon
FMRI is actively involved in clinical trials, focusing on innovative cancer treatments and improving patient outcomes. The institute collaborates with top global research organizations, ensuring patients have access to the latest treatments and cutting-edge therapies. With a multidisciplinary team of oncologists, researchers, and healthcare professionals, FMRI is committed to delivering personalized care, advancing cancer research, and setting new standards in oncology.
HCG - Healthcare Global Enterprises Ltd. (Multiple Locations)
HCG is actively engaged in clinical trials, focusing on personalized medicine and innovative cancer treatments. The network collaborates with leading national and international research institutions, ensuring patients have access to the latest therapeutic advancements. HCG’s multidisciplinary approach and state-of-the-art facilities make it a leader in cancer care, dedicated to improving patient outcomes and advancing the field of oncology through rigorous research and clinical excellence.
Manipal Hospitals (Multiple Locations)
Manipal Hospitals are actively involved in clinical trials, exploring new cancer treatments and enhancing existing protocols. The network collaborates with prominent research organizations worldwide, ensuring patients have access to the latest innovations in cancer care. With state-of-the-art facilities and a dedicated team of oncologists, researchers, and healthcare professionals, Manipal Hospitals are committed to delivering high-quality care, advancing cancer treatment, and contributing significantly to medical research.
Cancer remains a formidable challenge in India, but through the diligent efforts of top-tier institutions and the advancement of clinical trials, there is hope for better treatments and improved patient outcomes. The strides made in cancer research not only provide innovative therapies but also pave the way for a brighter future for patients and their families.
At Milaap, we understand the critical role that financial support plays in accessing these advanced treatments. By connecting patients with donors, we strive to ensure that everyone has the opportunity to benefit from the latest cancer therapies. Together, we can support these life-saving clinical trials and help patients receive the best possible care, ultimately contributing to the fight against cancer and the advancement of medical science in India. Start your fundraiser today!
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